Thermo-diffusion and non-uniform heat source/sink effects on hydromagnetic flow of Cu and TiO2 water - based nanofluid partially filled with a porous medium

The study of nanofluids is important due to its vast public health potential.There exist many biomedical applications for nanofluids including drug delivery, magnetic cell separation, hyperthermia testing, photoablation therapy, biosensor development, bone-substituting implants, bioimaging, cell labeling, and gene delivery.Nanofluids are useful in

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Deliberation and Automaticity in Habitual Acts

Most philosophers and psychologists assume that habitual acts do not ensue from deliberation, but are direct responses to the circumstances: habit essentially involves a variety of automaticity.My objective in this paper is to show that this view is unduly restrictive.A habit can explain an act in various ways.Pointing to the operation of automatic

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Comparing neural sentence encoders for topic segmentation across domains: not your typical text similarity task

Neural sentence encoders (NSE) are effective in many NLP tasks, including topic segmentation.However, no systematic comparison of their performance in topic segmentation has been performed.Here, we present such a comparison, using supervised and unsupervised segmentation models based on NSEs.We first compare results with baselines, showing that the

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Substrate-induced unfolding of protein disulfide isomerase displaces the cholera toxin A1 subunit from its holotoxin.

To generate a cytopathic effect, the catalytic A1 subunit of cholera toxin (CT) must be separated from the rest of the toxin.Protein disulfide isomerase (PDI) is thought to mediate CT disassembly by acting Lumber Support as a redox-driven chaperone that actively unfolds the CTA1 subunit.Here, we show that PDI itself unfolds upon contact with CTA1.T

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